- Breast-feeding
- Pregnancy
- Severe somatic symptom disorders
- Acute conditions of chronic diseases
- Local inflammation
- Dermatological diseases in the injection area
- Problems with the functioning of the immune system
- Tendency to have allergic reactions
- Individual intolerance to the components of the drug
- The likelihood of scar formation
- Previous introduction of another gel into the injection area
- Infectious diseases
- Face polish done less than a month before the procedure